Veterinary Chemical · Generic
Antibiotic disc Tigecycline TGC
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Antibiotic discs impregnated with Tigecycline (TGC) are laboratory tools used for antimicrobial susceptibility testing (AST). They are not intended for direct treatment, but rather to determine if specific multidrug-resistant (MDR) bacteria affecting animals are sensitive to the drug prior to prescribing.
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Specs & features.
Tigecycline (TGC) is a broad-spectrum, first-in-class glycylcycline antibiotic, structurally related to minocycline within the tetracycline class. It was developed to overcome classical tetracycline resistance mechanisms like ribosomal protection and active drug efflux pumps.
No specifications have been listed.
- Standardized Potency: Standard Tigecycline discs contain 15 µg (micrograms) of the antibiotic.
- Natural Resistances: It is generally not effective against Pseudomonas, Proteus, and Providencia species.
- Mechanism of Action (AST): Like its therapeutic function, the disc diffuses through the agar to inhibit bacterial protein synthesis by binding reversibly to the 30S ribosomal subunit, preventing bacterial growth.
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